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이달의 논문 2026년 3월
등록일 : 2026.04.13
. 2026 Mar;42(3):237-241.
 doi: 10.1055/a-2616-4817. Epub 2025 May 22.

Ultrasonographic Quantification of Blood Flow in Microsurgical Breast Reconstruction: Correlation with Indocyanine Green Angiography

Affiliations 

Abstract

Although autologous breast reconstruction using the deep inferior epigastric artery perforator (DIEP) flap is a standard procedure, flap perfusion-associated complications remain a concern. This study aimed to investigate the correlation between blood flow information obtained through color Doppler ultrasonography (CDU) and flap perfusion assessed by indocyanine green (ICG) angiography.This prospective study included 30 female patients who underwent DIEP flap breast reconstruction between August 2023 and June 2024. Preoperative flow parameters, including arterial peak velocity, arterial volume flow, and venous peak velocity, were measured using CDU. Flap perfusion was evaluated using ICG angiography.The study demonstrated a positive correlation between venous flow and overall flap blood flow. Arterial peak velocity (r = 0.368, p = 0.046), arterial volume flow (r = 0.455, p = 0.011), and venous peak velocity (r = 0.399, p = 0.029) all showed significant associations with ICG-stained area percentages. These findings suggest that venous flow data can provide valuable information for predicting flap viability.This study demonstrates a significant correlation between flow information obtained through CDU and flap perfusion assessed via ICG angiography in patients undergoing DIEP flap breast reconstruction. Both arterial and venous flow data were shown to be crucial for predicting flap viability, with venous flow exhibiting a notable positive correlation with flap blood flow.

 

 

. 2026 Mar 1;157(3):516-526.
 doi: 10.1097/PRS.0000000000012387. Epub 2025 Aug 13.

Skeletal Stability of Occlusal Plane Rotational Orthognathic Surgery: A Cephalometric Analysis

Affiliations 

Abstract

Background: This study describes the long-term skeletal outcomes of occlusal plane rotational orthognathic surgery, shifting from traditional maxillomandibular complex advancement or setback by tailoring the direction and magnitude of rotation based on clinical and occlusal characteristics.

Methods: Patients undergoing maxillomandibular complex rotation by means of Le Fort I osteotomy and bilateral sagittal split ramus osteotomy were divided into 4 groups reflecting distinct occlusal and clinical characteristics: group A (class III malocclusion, posterior impaction with clockwise rotation); group B (cleft-related class III malocclusion, anterior lengthening with clockwise rotation); group C (class II malocclusion with sleep apnea, posterior lengthening with counterclockwise rotation); and group D (class II malocclusion with vertical maxillary excess, anterior impaction with counterclockwise rotation). Cephalometric landmarks were analyzed preoperatively, immediately postoperatively, and 3 years postoperatively. Postsurgical relapse was categorized as clinically insignificant (<2 mm/<2 degrees), potentially significant (2 to 4 mm/2 to 4 degrees), and highly significant (>4 mm/>4 degrees).

Results: The study included 76 patients (group A, 29 patients; group B, 22 patients; group C, 15 patients; and group D, 10 patients), with a mean evaluation period of 5.03 days immediately postoperatively and 36.5 months at 3 years postoperatively. Group B exhibited significant horizontal and vertical relapse at the cephalometric A point, with 54.5% showing potentially significant horizontal relapse and 45.5% showing vertical relapse. At the cephalometric B point, 3.4% of group A, 31.8% of group B, and 13.3% of group C demonstrated potentially significant vertical changes.

Conclusion: Occlusal plane rotational orthognathic surgery provides reliable skeletal stability when tailored to distinct clinical contexts, offering a versatile approach for aesthetic and functional correction.

 

 

. 2026 Mar 27;53(2):178-190.
 doi: 10.1055/a-2798-0198. eCollection 2026 Mar.

State-of-the-Art Medical Imaging Supporting Supermicrosurgery: A Scoping Review, Practical Guidelines, and Illustrative Case Report

Affiliations 

Abstract

In the era of supermicrosurgery, clinicians need more precise imaging modalities to know the exact microvascular and lymphatic anatomy of the patient. The goal of this review is to answer the research question "What are the state-of-the-art medical imaging modalities supporting supermicrosurgery?" This study is a scoping review and case report. Computed tomography angiography (CTA) and magnetic resonance angiography (MRA) are well-known current standard imaging modalities in flap surgery. In lymphatic surgery, lymphoscintigraphy is the gold standard. (Ultra)high-frequency ultrasound (UHFUS) has taken a major role in preoperative planning of flap surgery and lymphatic surgery. Practical guidelines on the use of UHFUS in flap planning and lymphatic surgery are described in this review article. Indocyanine green angiography and near-infrared fluorescent lymphography have also become key elements in modern flap surgery and lymphatic surgery. Moreover, contrast-enhanced magnetic resonance lymphography produces high-resolution imaging of superficial as well as deep lymphatic vessels. Laser tomography and photoacoustic imaging are promising experimental imaging techniques in lymphatic surgery. This review article describes and compares possible imaging modalities for preoperative planning and intraoperative guidance with the aims of enhancing surgical outcomes, reducing operative time, and preventing complications in supermicrosurgery. Moreover, a case report is described in order to illustrate the practical imaging work-up in daily practice.

Keywords: extremity/lymphedema; imaging; medical imaging; microsurgery; reconstructive surgery; research/experimental; supermicrosurgery.

 

 

. 2026 Mar 3;53(4):361-368.
doi: 10.1055/a-2777-5624. eCollection 2026 Jul.

Peripheral Lymphatic Shunts for Protein-Losing Enteropathy in a Child with THSD1 Mutation: A Case Report

Affiliations

Affiliations

  • 1Division of Plastic Surgery, Department of Surgery, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.
  • 2Department of Plastic Surgery and Burn Unit, King Saud Medical City, Riyadh, Saudi Arabia.
  • 3Division of Plastic Surgery, Department of Surgery, King Saud bin Abdulaziz University for Health and Sciences, Riyadh, Saudi Arabia.
  • 4Beauty for Life Center in Yas Clinic-Abu Dhabi Stem Cell Center (ADSCC), Abu Dhabi, United Arab Emirates.
  • 5Department of Plastic and Reconstructive Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.

Abstract

Protein-losing enteropathy (PLE) is a rare disorder characterized by abnormal protein loss through the gastrointestinal tract, often leading to hypoalbuminemia and malnutrition. This case report describes the successful surgical management of chronic lower limb lymphedema and PLE in a 7-year-old male with a thrombospondin type 1 domain-containing 1 (THSD1) mutation, unresponsive to conventional therapies. Despite aggressive nutritional support, including albumin infusions, the patient experienced persistent hypoalbuminemia and ongoing protein loss. Imaging revealed significant lymphatic dysfunction, prompting lymphovenous bypass and lymph node-vein anastomosis (LNVA). Postoperatively, serum albumin levels improved from 1.5 to 3.2 g/dL, limb circumference decreased, and alpha-1 antitrypsin levels normalized. However, a 3-year follow-up revealed a relapse of hypoalbuminemia following an upper respiratory infection, underscoring the need for additional interventions in growing pediatric patients. This case strengthens the potential of lymphatic surgery in addressing PLE-related lymphatic dysfunction when medical treatments fail and emphasizes the need for further research to confirm the efficacy of this approach.

Keywords: THSD1 mutation; hypoalbuminemia; lymph node to vein anastomosis; lymphatic dysfunction; lymphatic surgery; lymphoscintigraphy; lymph–venous bypass; pediatric lymphedema; protein-losing enteropathy.

 

 

. 2026 Mar;25(1):109-117.
doi: 10.1177/15347346231195944. Epub 2023 Aug 22.

The Role of Escin as a Topical Agent for Lymphedema Treatment in a Rat Model

Affiliations

Abstract

Escin, a naturally derived material isolated from horse chestnut, is used as an anti-inflammatory and anti-edema agent. This study aimed to evaluate its effects on lymphedema in a rat tail model. We divided the rats into five groups. The treatment groups received topical application of escin gel at concentrations of 20%, 10%, 2%, and 0.5% for 4 weeks. The fifth group served as a control. We performed volumetric (water displacement) tests, H&E staining, and LYVE-1 immunohistochemical staining, followed by statistical evaluation. All treatment groups showed significant volumetric reductions compared with the control group, but no significant differences were observed between the treatment groups. H&E staining showed a significant reduction in dermal thickness in the 20%, 10%, and 2% escin treatment groups compared to the control group. Within the treatment groups, the 2% escin group showed a significant difference compared with the 20% and 10% escin groups (p = 0.021 for both). LYVE-1 immunohistochemical staining revealed a significantly higher mean lymphatic vessel count in the 2% escin group compared with the 20%, 10%, and 0.5% escin-treated groups and the control group (p = 0.019, p = 0.025, p = 0.019, and p = 0.032 respectively). Topical escin applied to a rat tail model of acute lymphedema resulted in a significant reduction in tail volume, reduced dermal thickness, and increased lymphatic structures. The 2% escin concentration may be the optimal dose for improving lymphedema in this model. Further research is warranted to explore the clinical application of escin in patients with lymphedema.

Keywords: escin; lymphedema; topical treatment for lymphedema.

 

 

 

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